SS-31 10mg

Description

SS-31 10mg is a 10mg vial of SS-31, a mitochondria-targeted tetrapeptide, made in the USA and supplied as freeze-dried powder. It’s for in-vitro and lab research only.

On older labels you may see this listed simply as 31. It’s the same peptide, SS-31.

What is SS-31?

SS-31, also called elamipretide, is a four-amino-acid peptide: D-Arg-Dmt-Lys-Phe-NH2. It alternates positive charges with aromatic rings, a design that lets it slip through cell membranes and collect in mitochondria.

Once there, it binds cardiolipin, a fat that’s found almost only in the inner mitochondrial membrane and that holds the energy-making machinery in place.

SS-31 mechanism of action

Cardiolipin holds together the protein complexes that make ATP in mitochondria. When it’s oxidized, those complexes work less well and leak more free radicals.

SS-31 binds cardiolipin and protects it, which in lab studies kept the electron transport chain working more efficiently and cut oxidative damage. It doesn’t depend on the membrane voltage to get into mitochondria, which sets it apart from other targeted antioxidants.

SS-31 10mg specifications

• Compound: SS-31
• CAS number: 736992-21-5
• Molecular formula: C32H49N9O5
• Molar mass: 639.8 g/mol
• Sequence: D-Arg-Dmt-Lys-Phe-NH2
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• Vial size: 3mL glass vial
• Purity: 99% or higher by HPLC
• Made in: USA
• SKU: CP-SS31-10
• Use: laboratory research only

What the research says about SS-31

Hazel Szeto and Peter Schiller designed it in the early 2000s; SS stands for Szeto-Schiller. Stealth BioTherapeutics took it into clinical trials for mitochondrial diseases, including primary mitochondrial myopathy and Barth syndrome.

It’s one of the few mitochondria-targeted peptides with real human trial data. This vial is research material, not the clinical product.

For the original studies, try this PubMed search.

How SS-31 compares

Here’s how SS-31 10mg fits among related compounds. SS-31 targets cardiolipin on the inner mitochondrial membrane. By comparison:

• Epithalon is the tetrapeptide Ala-Glu-Asp-Gly, studied for telomerase activity
• NAD+ is the coenzyme behind cell energy and sirtuin activity, whose levels fall with age
• Glutathione is the cell’s main antioxidant tripeptide
• MOTS-c is a 16-amino-acid peptide coded in mitochondrial DNA, studied for glucose use in muscle
• GHK-Cu is the copper-binding tripeptide studied for collagen and skin repair

Aging research splits into a few processes, and each of these compounds targets one: telomeres, cell energy, mitochondria, oxidative stress or tissue repair. See them all on our anti-aging peptides page.

How to reconstitute SS-31 10mg

Concentration is the amount in the vial divided by the volume of water you add. With 10mg of powder in this vial:

• 1mL of bacteriostatic water gives 10mg/mL
• 2mL of bacteriostatic water gives 5mg/mL
• 3mL of bacteriostatic water gives 3.33mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later. The vial itself holds 3mL, so that’s the upper limit.

Use sterile bacteriostatic water, like our 10mL bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll the vial gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.

SS-31 10mg storage and shelf life

The dry powder keeps best cold. A freezer at -20°C is ideal for long-term storage, and a fridge works for a few weeks. After reconstitution, store it in the fridge and finish it within roughly four weeks.

Vials are small and easy to knock over or misplace. Our 6 vial and 10 vial containers keep a whole study’s worth together.

SS-31 10mg purity and lab testing

Every batch of SS-31 10mg is made in the USA and checked by an independent U.S. lab for three things: that it’s the right compound, that the amount matches the label and that purity is 99% or better by HPLC.

Scroll through the photos at the top of the page and you’ll find the current batch’s certificate of analysis. We post the actual report, so you can check the figures yourself.

Batches are also screened for endotoxins, heavy metals and sterility. Those contaminant checks matter as much as purity for cell work, where a small amount of endotoxin can skew results.

Other SS-31 strengths

• SS-31 10mg (this page): $59.00, about $5.90 per mg
• SS-31 30mg: $160.00, about $5.33 per mg
• SS-31 50mg: $180.00, about $3.60 per mg

SS-31 10mg is the smallest size. It’s the one to start with for a pilot run or when you’re testing a new protocol.

Often ordered with SS-31 10mg

• 5-Amino-1MQ 10mg, an NNMT inhibitor
• Epithalon 50mg, a tetrapeptide
• MOTS-c 40mg, a mitochondrial peptide
• NAD+ 500mg, a coenzyme
• Methylcobalamin B12 10mg/mL (10mL), a ready-made 10mL liquid

Browse the full anti-aging peptides range, or see every vial on our research peptides page.

SS-31 10mg questions

How much is in the SS-31 10mg vial?

10mg of freeze-dried powder. The amount is printed on the label.

Where is it made?

In the USA. We only sell U.S.-made research products, and each batch is tested by a U.S. lab.

Is there a certificate of analysis for SS-31 10mg?

Yes. The current batch’s COA is in the image gallery on this page.

What do I mix SS-31 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer for long-term storage or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.

Buy SS-31 10mg online

SS-31 10mg is in stock at $59.00. Add it to the cart and check out in a couple of minutes.

Need more for the same project? See the rest of our anti-aging peptides.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.