Description
Our Epithalon 10mg vial holds 10mg of lyophilized Epithalon, a synthetic tetrapeptide, made and tested in the USA. It’s for in-vitro and lab research only.
About Epithalon
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide based on epithalamin, a pineal gland extract. Vladimir Khavinson’s group developed it.
It’s studied in aging research.
How Epithalon acts in the lab
Epitalon is modeled on epithalamin, a peptide extract of the pineal gland. The pineal gland produces melatonin, and the original work looked at how it changed with age.
In cell culture, Khavinson’s group reported that epitalon switched on telomerase, the enzyme that rebuilds the protective caps on chromosome ends. Its other reported effects include normalizing melatonin rhythms in older animals.
Epithalon 10mg technical data
- Compound: Epithalon
- Also known as: Epitalon, AEDG
- CAS number: 307297-39-8
- Molecular formula: C14H22N4O9
- Molar mass: 390.3 g/mol
- Sequence: Ala-Glu-Asp-Gly
- Amount: 10mg per vial
- Form: lyophilized (freeze-dried) powder
- Vial size: 3mL glass vial
- Purity: 99% or higher by HPLC
- Made in: USA
- SKU: CP-EPI-10
- Use: laboratory research only
What the research says about Epithalon
Khavinson and colleagues reported that epitalon activated telomerase and lengthened telomeres in human fibroblast cultures (2003).
Rodent studies from the same group reported longer lifespans and fewer tumors.
For the original studies, try this PubMed search.
Epithalon compared with similar compounds
Epithalon 10mg is easier to place once you see it next to the compounds it’s usually compared with. Epithalon is the tetrapeptide Ala-Glu-Asp-Gly, studied for telomerase activity. The others:
- NAD+ is the coenzyme behind cell energy and sirtuin activity, whose levels fall with age
- SS-31 targets cardiolipin on the inner mitochondrial membrane
- Glutathione is the cell’s main antioxidant tripeptide
- MOTS-c is a 16-amino-acid peptide coded in mitochondrial DNA, studied for glucose use in muscle
- GHK-Cu is the copper-binding tripeptide studied for collagen and skin repair
Aging research splits into a few processes, and each of these compounds targets one: telomeres, cell energy, mitochondria, oxidative stress or tissue repair. See them all on our anti-aging peptides page.
Lab-tested Epithalon 10mg
We only sell U.S.-made products, and Epithalon 10mg is no exception. Each batch is tested by an outside U.S. lab for identity, content and purity, with a 99%+ HPLC purity standard.
The certificate of analysis for the batch in stock is posted in the product gallery above. Click through the images and you’ll see the lab report with its date and numbers.
On top of purity, each batch is screened for endotoxins, heavy metals and sterility. For cell culture work that screen is often the more important number.
Reconstituting Epithalon 10mg
Concentration is the amount in the vial divided by the volume of water you add. With 10mg of powder in this vial:
- 1mL of bacteriostatic water gives 10mg/mL
- 2mL of bacteriostatic water gives 5mg/mL
- 3mL of bacteriostatic water gives 3.33mg/mL
Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it. The vial itself holds 3mL, so that’s the upper limit.
Use sterile bacteriostatic water, like our 10mL bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll the vial gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.
How to store Epithalon 10mg
Freeze-dried Epithalon 10mg handles room temperature fine during shipping, but for anything longer keep it in a freezer at -20°C, away from light. Once mixed, keep it in the fridge at 2 to 8°C and use it within about four weeks.
Vials are small and easy to knock over or misplace. Our 6 vial and 10 vial containers keep a whole study’s worth together.
Choosing an Epithalon strength
- Epithalon 10mg (this page): $45.00, about $4.50 per mg
- Epithalon 50mg: $110.00, about $2.20 per mg
Epithalon 10mg is the entry size, handy when you only need a little or want to try Epithalon before committing to a bigger vial.
Related to Epithalon 10mg
- SS-31 10mg, a mitochondrial peptide
- Buffered NAD+ 500mg, a coenzyme
- ATX-304 Capsules 100mg (60 Count), an oral capsule format
- FOXO4-DRI 10mg, a senolytic peptide
- MOTS-c 40mg, a mitochondrial peptide
Browse the full anti-aging peptides range, or see every vial on our research peptides page.
Epithalon 10mg FAQ
How much is in the Epithalon 10mg vial?
10mg of freeze-dried powder. The amount is printed on the label.
How should I store it?
Keep sealed vials in the freezer for long-term storage or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.
Can Epithalon be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Is Epithalon 10mg in stock?
Yes. Epithalon 10mg is in stock and ships from the U.S.
Where is it made?
In the USA. We only sell U.S.-made research products, and each batch is tested by a U.S. lab.
Buy Epithalon 10mg from Certified Peptides
Ready to order? This vial costs $45.00, down from $54.00 and is in stock. Add it to your cart and you’re done. Need water to mix it? Add a 10mL bacteriostatic water to the same order.
Need more for the same project? See the rest of our anti-aging peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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