Description
Our GLP3-R 60mg vial holds 60mg of lyophilized GLP3-R (retatrutide), a GIP, GLP-1 and glucagon receptor agonist, made and tested in the USA. It’s for in-vitro and lab research only.
What is GLP3-R (retatrutide)?
Retatrutide (LY3437943, often sold as GLP-3R) is a single peptide from Eli Lilly that acts on three receptors: GIP, GLP-1 and glucagon.
It’s still in clinical trials.
GLP3-R mechanism of action
Retatrutide hits three receptors with one peptide: GIP, GLP-1 and glucagon. The first two are incretins that boost glucose-dependent insulin release and, in GLP-1’s case, curb appetite and slow stomach emptying.
The glucagon part is the unusual bit. Glucagon raises energy expenditure and pushes the liver to burn fat, so pairing it with the incretins is meant to work on both sides of energy balance. That’s the main reason researchers compare it with the dual and single agonists.
GLP3-R 60mg product details
- Compound: GLP3-R (retatrutide)
- Also known as: LY3437943
- CAS number: 2381089-83-2
- Molar mass: 4,731.3 g/mol
- Structure: 39 amino acids with a fatty diacid side chain
- Amount: 60mg per vial
- Form: lyophilized (freeze-dried) powder
- Vial size: 3mL glass vial
- Purity: 99% or higher by HPLC
- Made in: USA
- SKU: CP-GLP3R-60
- Use: laboratory research only
Published GLP3-R studies
Jastreboff and colleagues reported in the New England Journal of Medicine (2023) a mean weight loss of up to 24% at 48 weeks in a phase 2 trial.
Phase 3 trials are under way.
To read the papers yourself, start with this PubMed search for Retatrutide.
GLP3-R 60mg vs related compounds
Labs choosing GLP3-R 60mg usually weigh it against a few close relatives. GLP3-R hits GLP-1, GIP and glucagon receptors, the triple agonist with the biggest phase 2 numbers so far, while:
- GLP1-S acts on the GLP-1 receptor only and lasts about a week, the most studied compound in the group
- GLP2-T adds GIP receptor activity to GLP-1, a dual agonist with larger weight effects than semaglutide in trials
- Cagrilintide works through amylin receptors instead of incretins, often studied next to or with semaglutide
The main difference between these compounds is which receptors they hit. Pick the one that matches the receptor question in your study, and use the others as comparisons. See them all on our GLP-1 peptides page.
GLP3-R 60mg reconstitution and concentration
Here’s the math for 60mg of powder:
- 2mL of bacteriostatic water gives 30mg/mL
- 3mL of bacteriostatic water gives 20mg/mL
Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it. The vial itself holds 3mL, so that’s the upper limit.
Bacteriostatic water is the usual choice. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.
Storing GLP3-R 60mg
Freeze-dried GLP3-R 60mg handles room temperature fine during shipping, but for anything longer keep it in a freezer at -20°C, away from light. Once mixed, keep it in the fridge at 2 to 8°C and use it within about four weeks.
If you keep several vials going at once, our 10 vial container keeps them upright and together on a fridge shelf, and spare 3mL vial caps protect the stoppers once the seals are off.
Lab-tested GLP3-R 60mg
We only sell U.S.-made products, and GLP3-R 60mg is no exception. Each batch is tested by an outside U.S. lab for identity, content and purity, with a 99%+ HPLC purity standard.
You don’t have to take our word for it. The certificate of analysis for the current batch is in the image gallery at the top of this page, next to the product photo, and it shows the test date and the results.
Purity isn’t the whole story, so batches are screened for endotoxins, heavy metals and sterility too. Write the batch number from the label into your notes so you can match results to the paperwork later.
Other GLP3-R strengths
- GLP3-R 10mg: $140.00, about $14.00 per mg
- GLP3-R 30mg: $200.00, about $6.67 per mg
- GLP3-R 40mg: $240.00, about $6.00 per mg
- GLP3-R 60mg (this page): $270.00, about $4.50 per mg
- GLP3-R 120mg: $450.00, about $3.75 per mg
For longer projects GLP3-R 60mg works out cheaper per milligram than the small vial, and you’ll reorder less often.
Related to GLP3-R 60mg
- GLP2-T 30mg, a GIP/GLP-1 agonist
- GLP3-R Cagri Blend 12.5mg/2.5mg, GLP3-R and Cagrilintide in one vial
- Cagri GLP1-S Blend 5mg/5mg, Cagrilintide and GLP1-S in one vial
- GLP1-S 10mg, a GLP-1 agonist
- Cagrilintide 10mg, an amylin analog
Browse the full GLP-1 peptides and weight loss peptides range, or see every vial on our research peptides page.
GLP3-R 60mg questions
How much is in the GLP3-R 60mg vial?
60mg of freeze-dried powder. The amount is printed on the label.
What is GLP3-R?
GLP3-R is our catalog name for retatrutide. The vial holds retatrutide as freeze-dried powder.
What do I mix GLP3-R 60mg with?
Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.
How should I store it?
Keep sealed vials in the freezer for long-term storage or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.
Can GLP3-R be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Buy GLP3-R 60mg from Certified Peptides
Order GLP3-R 60mg now for $270.00. It’s in stock, and checkout takes about two minutes.
Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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