Description
GLP3-R Cagri blend puts 12.5mg GLP3-R and 2.5mg Cagrilintide into one sealed vial, so you reconstitute once instead of two times. It’s made in the USA and sold for laboratory research only.
What the GLP3-R Cagri blend contains
Retatrutide (LY3437943, often sold as GLP-3R) is a single peptide from Eli Lilly that acts on three receptors: GIP, GLP-1 and glucagon.
Cagrilintide is a long-acting amylin analog from Novo Nordisk, given weekly. Amylin is a hormone released with insulin that slows stomach emptying and reduces appetite.
This blend puts the triple agonist next to an amylin analog. Amylin and the incretins reach appetite through different receptors, so labs combine them to see whether the effects add up, the same logic behind CagriSema.
The ratio is fixed at 12.5mg/2.5mg. Because everything is freeze-dried together, the ratio can’t drift the way it can when you mix separate vials. One reconstitution, one label, the same proportions in every draw.
How the GLP3-R Cagri blend works
Retatrutide hits three receptors with one peptide: GIP, GLP-1 and glucagon. The first two are incretins that boost glucose-dependent insulin release and, in GLP-1’s case, curb appetite and slow stomach emptying.
Amylin is released by the pancreas together with insulin. It slows stomach emptying, damps glucagon after meals and signals fullness through the brainstem.
GLP3-R Cagri blend product details
- GLP3-R (retatrutide), 12.5mg: CAS 2381089-83-2, 4,731.3 g/mol
- Cagrilintide, 2.5mg: CAS 1415456-99-3, 4,409 g/mol
- Amount: 15mg in total (12.5mg/2.5mg per vial)
- Form: lyophilized (freeze-dried) powder
- Vial size: 3mL glass vial
- Purity: 99% or higher by HPLC
- Made in: USA
- SKU: CP-GLP3R-CAGRI
- Use: laboratory research only
Published GLP3-R Cagri blend studies
Jastreboff and colleagues reported in the New England Journal of Medicine (2023) a mean weight loss of up to 24% at 48 weeks in a phase 2 trial.
Phase 3 trials are under way.
Enebo and colleagues reported in The Lancet (2021) that cagrilintide with semaglutide gave more weight loss than either alone.
Phase 3 REDEFINE trials followed.
The primary literature is on PubMed. Here’s a search for GLP3-R and Cagrilintide studies to start from.
How to reconstitute GLP3-R Cagri blend
The amount of liquid you add sets the concentration. For a vial holding 15mg:
- 1mL of bacteriostatic water gives 15mg/mL
- 2mL of bacteriostatic water gives 7.5mg/mL
- 3mL of bacteriostatic water gives 5mg/mL
Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it. The vial itself holds 3mL, so that’s the upper limit.
Most labs use sterile bacteriostatic water; we sell it in 10mL and 30mL vials. Warm the sealed vial to room temperature, add the water slowly along the glass wall and swirl gently until it’s clear. Never shake it.
Storing GLP3-R Cagri blend
Store sealed vials of GLP3-R Cagri blend in the freezer (-20°C) or the fridge (2 to 8°C), out of direct light. Mixed solution goes back in the fridge and should be used within about 28 days.
If you keep several vials going at once, our 10 vial container keeps them upright and together on a fridge shelf, and spare 3mL vial caps protect the stoppers once the seals are off.
Lab-tested GLP3-R Cagri blend
GLP3-R Cagri blend is made in the USA, and every batch goes to an independent U.S. laboratory before it’s sold. The lab confirms identity, measures the content and checks purity by HPLC. Our standard is 99% or higher.
The certificate of analysis for the batch in stock is posted in the product gallery above. Click through the images and you’ll see the lab report with its date and numbers.
On top of purity, each batch is screened for endotoxins, heavy metals and sterility. For cell culture work that screen is often the more important number.
How many GLP3-R Cagri blend vials do you need?
Work out the total amount before you order. Add up what each arm of the study uses across every time point, then divide by 15mg. Round up by one vial so a spoiled sample or a repeat run doesn’t stall the project.
Mix one vial at a time and keep the rest sealed in the freezer. Dry powder keeps far longer than solution, so there’s no reason to reconstitute everything at the start.
If you order more than one vial, check that the batch numbers match before you start. Running a whole study on one batch removes one variable.
Other GLP-1 peptides to look at
- GLP1-S 5mg, a GLP-1 agonist
- GLP3-R 40mg, a triple agonist
- Cagrilintide 10mg, an amylin analog
- Cagri GLP1-S Blend 5mg/5mg, Cagrilintide and GLP1-S in one vial
- GLP2-T 10mg, a GIP/GLP-1 agonist
Browse the full GLP-1 peptides and weight loss peptides range, or see every vial on our research peptides page.
GLP3-R Cagri blend FAQ
How much is in the GLP3-R Cagri blend vial?
12.5mg of GLP3-R and 2.5mg of Cagrilintide, freeze-dried together. The amount is printed on the label.
Is there a certificate of analysis for GLP3-R Cagri blend?
Yes. The current batch’s COA is in the image gallery on this page.
What do I mix GLP3-R Cagri blend with?
Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.
How should I store it?
Keep sealed vials in the freezer for long-term storage or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.
Can GLP3-R Cagri blend be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Order GLP3-R Cagri blend today
Ready to order? GLP3-R Cagri blend costs $200.00 and is in stock. Add it to your cart and you’re done. Need water to mix it? Add a 10mL bacteriostatic water to the same order.
Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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