Description
The BPC-157 TB-500 blend from Certified Peptides holds 10mg BPC-157 and 10mg TB-500, freeze-dried together in one vial. It’s made in the USA and sold for laboratory research only.
What the BPC-157 TB-500 blend contains
BPC-157 is a 15-amino-acid peptide based on a fragment of body protection compound, a protein first found in gastric juice. It’s one of the most widely studied research peptides, almost entirely in rodents.
TB-500 here means thymosin beta-4, a 43-amino-acid protein found in nearly every cell in the body, with high levels in platelets and white blood cells. Inside the cell it binds actin, the protein cells use to change shape and move.
BPC-157 and TB-500 are the two most studied repair peptides, and they work through different routes: BPC-157 through blood vessel growth and nitric oxide signaling, TB-500 through actin and cell movement.
The ratio is fixed at 10mg/10mg. Because everything is freeze-dried together, the ratio can’t drift the way it can when you mix separate vials. One reconstitution, one label, the same proportions in every draw.
Mechanisms behind the BPC-157 TB-500 blend
Nobody has pinned down a single receptor for BPC-157. Lab studies point to several pathways: it raises VEGF receptor expression, which feeds blood vessel growth, it interacts with the nitric oxide system, and it increases growth hormone receptor levels in tendon cells.
Thymosin beta-4’s main job is holding on to G-actin, the single building blocks of the cell’s internal scaffolding. By controlling how much actin is free to polymerize, it controls how cells move and change shape.
BPC-157 TB-500 blend product details
- BPC-157, 10mg: CAS 137525-51-0, C62H98N16O22, 1,419.5 g/mol
- TB-500 (thymosin beta-4), 10mg: CAS 77591-33-4, C212H350N56O78S, 4,963.4 g/mol
- Amount: 20mg in total (10mg/10mg per vial)
- Form: lyophilized (freeze-dried) powder
- Vial size: 3mL glass vial
- Purity: 99% or higher by HPLC
- Made in: USA
- SKU: CP-BPCTB-20
- Use: laboratory research only
BPC-157 TB-500 blend research
Most of the work comes from Predrag Sikiric’s group at the University of Zagreb. Their rodent studies report faster healing of tendon, ligament, muscle and gut injuries, and Mikus and colleagues described improved burn wound healing in mice.
Chang and colleagues reported in 2011 that BPC-157 raised growth hormone receptor expression in rat tendon fibroblasts. Controlled human data are very limited.
Goldstein and colleagues reviewed thymosin beta-4’s role in wound repair in 2012, covering faster closure of skin wounds and new blood vessel growth in animal models.
Bock-Marquette and colleagues reported in Nature (2004) that thymosin beta-4 improved heart cell survival after injury in mice.
To read the papers yourself, start with this PubMed search for BPC-157 and TB-500.
BPC-157 TB-500 blend purity and lab testing
Every batch of BPC-157 TB-500 blend is made in the USA and checked by an independent U.S. lab for three things: that it’s the right compound, that the amount matches the label and that purity is 99% or better by HPLC.
Scroll through the photos at the top of the page and you’ll find the current batch’s certificate of analysis. We post the actual report, so you can check the figures yourself.
On top of purity, each batch is screened for endotoxins, heavy metals and sterility. For cell culture work that screen is often the more important number.
How to reconstitute BPC-157 TB-500 blend
Here’s the math for 20mg of powder:
- 1mL of bacteriostatic water gives 20mg/mL
- 2mL of bacteriostatic water gives 10mg/mL
- 3mL of bacteriostatic water gives 6.67mg/mL
Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label. The vial itself holds 3mL, so that’s the upper limit.
Bacteriostatic water is the usual choice. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.
BPC-157 TB-500 blend storage and shelf life
Freeze-dried BPC-157 TB-500 blend handles room temperature fine during shipping, but for anything longer keep it in a freezer at -20°C, away from light. Once mixed, keep it in the fridge at 2 to 8°C and use it within about four weeks.
A 6 vial container keeps open and sealed vials upright and apart, which makes the fridge a lot easier to manage. For a bigger collection, the Big Everything Box holds vials and supplies in one latching case.
Related to BPC-157 TB-500 blend
- BPC-157 TB-500 Capsules 500mcg/500mcg (60 Count), an oral capsule format
- GLOW KLOW Capsules (60 Count), an oral capsule format
- TB-500 10mg (Thymosin Beta-4), a thymosin beta-4 peptide
- K-Copper Blend 70mg (GHK-Cu, KPV), GHK-Cu and KPV in one vial
- LL-37 5mg, an antimicrobial peptide
Browse the full healing and recovery peptides range, or see every vial on our research peptides page.
BPC-157 TB-500 blend FAQ
How much is in the BPC-157 TB-500 blend vial?
10mg of BPC-157 and 10mg of TB-500, freeze-dried together. The amount is printed on the label.
Where is it made?
In the USA. We only sell U.S.-made research products, and each batch is tested by a U.S. lab.
Is there a certificate of analysis for BPC-157 TB-500 blend?
Yes. The current batch’s COA is in the image gallery on this page.
What do I mix BPC-157 TB-500 blend with?
Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.
How should I store it?
Keep sealed vials in the freezer for long-term storage or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.
Buy BPC-157 TB-500 blend from Certified Peptides
Order BPC-157 TB-500 blend now for $110.00. It’s in stock, and checkout takes about two minutes.
Need more for the same project? See the rest of our healing and recovery peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
Reviews
There are no reviews yet.