Description
IGF-1 LR3 1mg from Certified Peptides is 1mg of IGF-1 LR3 in a sealed glass vial. IGF-1 LR3 is an IGF-1 analog. It’s sold for laboratory research only.
What is IGF-1 LR3?
IGF-1 LR3 is an 83-amino-acid analog of IGF-1 with an arginine swap at position 3 and a 13-amino-acid extension. Those changes stop it binding IGF binding proteins, so it stays active much longer.
It’s widely used in cell culture media.
IGF-1 LR3 mechanism of action
IGF-1 is the hormone that carries out much of growth hormone’s effect on cells. Most of it in the body is bound by IGF binding proteins, which hold it inactive.
LR3 has an arginine in place of glutamate at position 3 plus a 13-residue extension. Binding proteins barely recognize it, so it stays free and active far longer. That’s why it’s the standard IGF-1 in cell culture media.
IGF-1 LR3 1mg product details
- Compound: IGF-1 LR3
- Also known as: Long R3 IGF-1
- CAS number: 946870-92-4
- Molecular formula: C400H625N111O115S9
- Molar mass: 9,111 g/mol
- Structure: 83 amino acids
- Amount: 1mg per vial
- Form: lyophilized (freeze-dried) powder
- Vial size: 3mL glass vial
- Purity: 99% or higher by HPLC
- Made in: USA
- SKU: CP-IGFLR3-1
- Use: laboratory research only
What the research says about IGF-1 LR3
It was developed for cell culture in the 1990s.
In cell culture it’s several times more potent than IGF-1.
The primary literature is on PubMed. Here’s a search for IGF-1 LR3 studies to start from.
How IGF-1 LR3 compares
Here’s how IGF-1 LR3 1mg fits among related compounds. IGF-1 LR3 is an 83-amino-acid IGF-1 analog that avoids binding proteins and lasts for hours. By comparison:
- IGF-1 DES is IGF-1 missing three residues, potent locally but cleared faster than IGF-1 LR3
- MGF is the E-domain peptide from the muscle-specific IGF-1 splice variant
- PEG-MGF is MGF with a PEG chain added so it lasts much longer
These sit downstream of growth hormone, on the IGF-1 side of the axis. They differ in how they avoid binding proteins, how long they last and which receptor they rely on. See them all on our growth hormone peptides page.
IGF-1 LR3 1mg reconstitution and concentration
Concentration is the amount in the vial divided by the volume of water you add. With 1mg of powder in this vial:
- 1mL of bacteriostatic water gives 1mg/mL
- 2mL of bacteriostatic water gives 0.5mg/mL
Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label. The vial itself holds 3mL, so that’s the upper limit.
Most labs use sterile bacteriostatic water; we sell it in 10mL and 30mL vials. Warm the sealed vial to room temperature, add the water slowly along the glass wall and swirl gently until it’s clear. Never shake it.
Storing IGF-1 LR3 1mg
Freeze-dried IGF-1 LR3 1mg handles room temperature fine during shipping, but for anything longer keep it in a freezer at -20°C, away from light. Once mixed, keep it in the fridge at 2 to 8°C and use it within about four weeks.
A 6 vial container keeps open and sealed vials upright and apart, which makes the fridge a lot easier to manage. For a bigger collection, the Big Everything Box holds vials and supplies in one latching case.
How IGF-1 LR3 1mg is tested
IGF-1 LR3 1mg is made in the USA, and every batch goes to an independent U.S. laboratory before it’s sold. The lab confirms identity, measures the content and checks purity by HPLC. Our standard is 99% or higher.
Scroll through the photos at the top of the page and you’ll find the current batch’s certificate of analysis. We post the actual report, so you can check the figures yourself.
On top of purity, each batch is screened for endotoxins, heavy metals and sterility. For cell culture work that screen is often the more important number.
Other growth hormone peptides to look at
- GHRP-2 10mg, a GH releasing peptide
- CJC-1295 No DAC 10mg, a GHRH analog
- Sermorelin Capsules 1mg (60 Count), an oral capsule format
- Tesamorelin Ipamorelin Blend 13mg, Tesamorelin and Ipamorelin in one vial
- MK-777 Capsules 20mg (60 Count), an oral capsule format
Browse the full growth hormone peptides and healing and recovery peptides range, or see every vial on our research peptides page.
Common questions about IGF-1 LR3 1mg
How much is in the IGF-1 LR3 1mg vial?
1mg of freeze-dried powder. The amount is printed on the label.
Is there a certificate of analysis for IGF-1 LR3 1mg?
Yes. The current batch’s COA is in the image gallery on this page.
What do I mix IGF-1 LR3 1mg with?
Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.
How should I store it?
Keep sealed vials in the freezer for long-term storage or the fridge for a few weeks. Once mixed, refrigerate and use within about 28 days.
Can IGF-1 LR3 be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Buy IGF-1 LR3 1mg online
Order IGF-1 LR3 1mg now for $80.00. It’s in stock, and checkout takes about two minutes. Need water to mix it? Add a 10mL bacteriostatic water to the same order.
Need more for the same project? See the rest of our growth hormone peptides and healing and recovery peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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