Description
The KLOW blend 80mg from Certified Peptides holds 50mg GHK-Cu, 10mg BPC-157, 10mg TB-500 and 10mg KPV, freeze-dried together in one vial. It’s made in the USA and sold for laboratory research only.
Inside the KLOW blend 80mg
GHK-Cu is the tripeptide glycyl-histidyl-lysine bound to a copper ion. GHK occurs naturally in human plasma, saliva and urine, and its levels fall with age.
BPC-157 is a 15-amino-acid peptide based on a fragment of body protection compound, a protein first found in gastric juice. It’s one of the most widely studied research peptides, almost entirely in rodents.
TB-500 here means thymosin beta-4, a 43-amino-acid protein found in nearly every cell in the body, with high levels in platelets and white blood cells. Inside the cell it binds actin, the protein cells use to change shape and move.
KPV is the tripeptide lysine-proline-valine, the C-terminal end of alpha-melanocyte stimulating hormone. It keeps alpha-MSH’s anti-inflammatory activity without the pigment effects.
KLOW is GLOW with KPV added. KPV is a three-amino-acid fragment of alpha-MSH studied for calming inflammation, so KLOW covers the inflammatory side of repair as well.
KLOW is made as 50mg GHK-Cu, 10mg BPC-157, 10mg TB-500 and 10mg KPV, which adds up to the 80mg on the label. Because everything is freeze-dried together, the ratio can’t drift the way it can when you mix separate vials. One reconstitution, one label, the same proportions in every draw.
Mechanisms behind the KLOW blend 80mg
GHK binds copper tightly and can deliver it to cells. Copper is a cofactor for lysyl oxidase, the enzyme that cross-links collagen and elastin, and for antioxidant enzymes.
Nobody has pinned down a single receptor for BPC-157. Lab studies point to several pathways: it raises VEGF receptor expression, which feeds blood vessel growth, it interacts with the nitric oxide system, and it increases growth hormone receptor levels in tendon cells.
Thymosin beta-4’s main job is holding on to G-actin, the single building blocks of the cell’s internal scaffolding. By controlling how much actin is free to polymerize, it controls how cells move and change shape.
Alpha-MSH calms inflammation through melanocortin receptors. KPV is its last three amino acids and keeps much of that anti-inflammatory activity.
KLOW blend 80mg technical data
- GHK-Cu, 50mg: CAS 89030-95-5, C14H22CuN6O4, 401.9 g/mol
- BPC-157, 10mg: CAS 137525-51-0, C62H98N16O22, 1,419.5 g/mol
- TB-500 (thymosin beta-4), 10mg: CAS 77591-33-4, C212H350N56O78S, 4,963.4 g/mol
- KPV, 10mg: CAS 67727-97-3, C16H30N4O4, 342.4 g/mol
- Amount: 80mg in total (50mg/10mg/10mg/10mg per vial)
- Form: lyophilized (freeze-dried) powder
- Vial size: 3mL glass vial
- Purity: 99% or higher by HPLC
- Made in: USA
- SKU: CP-KLOW-80
- Use: laboratory research only
KLOW blend research
Loren Pickart, who first isolated GHK in 1973, has published reviews of its effects on collagen synthesis, wound contraction and gene expression in cell and animal studies.
Most of the work comes from Predrag Sikiric’s group at the University of Zagreb. Their rodent studies report faster healing of tendon, ligament, muscle and gut injuries, and Mikus and colleagues described improved burn wound healing in mice.
Goldstein and colleagues reviewed thymosin beta-4’s role in wound repair in 2012, covering faster closure of skin wounds and new blood vessel growth in animal models.
Dalmasso and colleagues reported in Gastroenterology (2008) that KPV reduced inflammation in mouse colitis models and was taken up through PepT1.
For the original studies, try this PubMed search.
How KLOW blend 80mg is tested
KLOW blend 80mg is made in the USA, and every batch goes to an independent U.S. laboratory before it’s sold. The lab confirms identity, measures the content and checks purity by HPLC. Our standard is 99% or higher.
Scroll through the photos at the top of the page and you’ll find the current batch’s certificate of analysis. We post the actual report, so you can check the figures yourself.
Batches are also screened for endotoxins, heavy metals and sterility. Those contaminant checks matter as much as purity for cell work, where a small amount of endotoxin can skew results.
How to reconstitute KLOW blend 80mg
Concentration is the amount in the vial divided by the volume of water you add. With 80mg of powder in this vial:
- 2mL of bacteriostatic water gives 40mg/mL
- 3mL of bacteriostatic water gives 26.67mg/mL
Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later. The vial itself holds 3mL, so that’s the upper limit.
Use sterile bacteriostatic water, like our 10mL bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll the vial gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.
Storing KLOW blend 80mg
Freeze-dried KLOW blend 80mg handles room temperature fine during shipping, but for anything longer keep it in a freezer at -20°C, away from light. Once mixed, keep it in the fridge at 2 to 8°C and use it within about four weeks.
A 6 vial container keeps open and sealed vials upright and apart, which makes the fridge a lot easier to manage. For a bigger collection, the Big Everything Box holds vials and supplies in one latching case.
Other skin and tanning peptides to look at
- GHK-Cu 100mg, a copper peptide
- GHK-Cu Raw Powder (1 Gram), bulk powder for formulation work
- Glow Tropic (10mL), a ready-made 10mL liquid
- Melanotan II 10mg (MT2), a melanocortin agonist
- Glutathione 1500mg, an antioxidant tripeptide
Browse the full skin and tanning peptides and healing and recovery peptides range, or see every vial on our research peptides page.
Common questions about KLOW blend 80mg
How much is in the KLOW blend 80mg vial?
50mg of GHK-Cu, 10mg of BPC-157, 10mg of TB-500 and 10mg of KPV, freeze-dried together. The amount is printed on the label.
Is KLOW blend 80mg in stock?
Yes. KLOW blend 80mg is in stock and ships from the U.S.
Where is it made?
In the USA. We only sell U.S.-made research products, and each batch is tested by a U.S. lab.
Is there a certificate of analysis for KLOW blend 80mg?
Yes. The current batch’s COA is in the image gallery on this page.
What do I mix KLOW blend 80mg with?
Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.
Buy KLOW blend 80mg online
Ready to order? KLOW blend 80mg costs $158.00 and is in stock. Add it to your cart and you’re done.
Need more for the same project? See the rest of our skin and tanning peptides and healing and recovery peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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